Area of research
Form & Buffer
This Kit contains: Lyophilized recombinant mouse LeptinR standard: 10ng/tube ×2, One 96-well plate precoated with anti- mouse LeptinR antibody, Sample diluent buffer: 30 ml, Biotinylated anti- mouse LeptinR antibody : 130 ul, dilution 1:100, Antibody diluent buffer: 12ml, Avidin-Biotin-Peroxidase Complex (ABC) : 130 ul, dilution 1:100, ABC diluent buffer: 12ml, TMB color developing agent: 10ml, TMB stop solution: 10ml
Store at 4 deg C for short term storage (4 months) or -20 deg C for long term storage (8 months)
Sensitivity: 156 pg/ml-10,000 pg/ml
E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays
ELISA Enzyme-linked immunosorbent assays Code 90320007 SNOMED,Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.